Hydrophobic interaction chromatography: a versatile method for ADC and protein analysis
Hydrophobic interaction chromatography (HIC) is a powerful method for analyzing and characterizing protein-based therapeutics under native conditions. It is the gold standard method for antibody-drug-conjugate (ADCs) analyses, but is equally suitable for the analysis of protein modifications such as oxidations, post-translational modifications or deamidations in protein therapeutics such as monoclonal antibodies (mAbs). This webinar will explain how HIC works, present application examples, and provide tips and tricks for method development.
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