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Anti-AANAT Rabbit Polyclonal Antibody

Dodávateľ: Thermo Scientific
This antibody does not react with rat, bovine, chicken or zebrafish samples. Arylalkylamine N-Acetyltransferase (AANAT) is the penultimate enzyme is melatonin synthesis. Hormonal melatonin has been implicated in sleep and circadian clock function. Large changes in the abundance of AANAT are believed to be responsible for the large day/night rhythms in melatonin synthesis in the pineal gland and retina (1,2). Most research shows that AANAT activity is regulated by controlling the steady-state levels of the protein. Recent research, however, suggests that another mechanism may also play a role in controlling melatonin production without altering AANAT protein and activity. This mechanism may explain the sudden physiological increase in circulating melatonin observed at the onset of the dark period in humans.

Type: Primary
Antigen: AANAT
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Primates, Human



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100 µL 100 µl PIEAPA116522 Blocked
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ŠPECIFIKÁCIE

Antigen symbol AANAT
Antigen name Serotonin N-acetyltransferase
Reactivity Primates, Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ImmunoFluorescence Yes
Antigen synonyms SNAT
Gene ID 15
Immunogen Human AANAT
Purification Antigen affinity chromatography
Form Liquid
Storage Buffer PBS, 0.1N acetic acid, 0.1% BSA, 0.05% thimerosal
Storage temperature Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Temperature Ice
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