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Anti-XRCC3 Rabbit Polyclonal Antibody

Dodávateľ: Thermo Scientific
This antibody is specific for XRCC3; no cross-reactivity was observed with XRCC2, RAD51, RAD51B, RAD51C, or RAD51D. This antibody is not recommended for ICC/IF applications. Suggested positive control: antigen standard for XRCC3 (transient overexpression lysate), TK6 lysates and 100 ug HeLa lysates. Five human RAD51 homologs have been identified: XRCC2, XRCC3, RAD51B, RAD51C, and RAD51D. Each of these homolgs interacts with one or more of the others, with all of the proteins involved in one complex or multiple smaller complexes. XRCC3 (x-ray cross complementing) was first identified as a human gene complementing the DNA damage sensitivity, chromosonal instability and impaired growth of the mutant hamster cell line irs1SF. This fact coupled with XRCC3 being a member of the RAD51 gene family have implied a role in the repair of DNA damage by homologous recombination.

Type: Primary
Antigen: XRCC3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human



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ŠPECIFIKÁCIE

Antigen symbol XRCC3
Antigen name X-ray Repair Complementing Defective Repair in Chinese Hamster cells 3
Reactivity Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ImmunoPrecipitation Yes
Antigen synonyms X ray repair cross complementing protein 3, X ray repair complementing defective repair in Chinese hamster cells 3, DNA repair protein XRCC3
Gene ID 7517
Concentration 1 mg/ml
Immunogen A synthetic partial peptide of human XRCC3.
Purification Antigen affinity chromatography
Form Liquid
Storage Buffer PBS, 0.05% sodium azide
Storage temperature -20° C, Avoid Freeze/Thaw Cycles
Shipping Temperature Ice
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