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Anti-53BP1 Rabbit Polyclonal Antibody

Dodávateľ: Thermo Scientific
Human samples have been tested in Western Blot and ICC/IF, and mouse samples have been tested in ICC/IF only. Suggested positive control: U205, 293T, and MO59K cell lysates and MEF lysates . P53-binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double-strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.

Type: Primary
Antigen: 53BP1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Rat, Mouse, Human



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100 µL 100 µl PIEAPA116566 Blocked
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ŠPECIFIKÁCIE

Antigen symbol 53BP1
Antigen name Tumor suppressor p53-binding protein 1
Reactivity Rat, Mouse, Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ImmunoChemistry Yes
ImmunoPrecipitation Yes
ImmunoFluorescence Yes
ChIP Yes
Antigen synonyms TP53BP1, p202
Gene ID 7158, 27223
Concentration 1 mg/ml
Immunogen Synthetic peptide of human tumor protein p53 binding protein 1 region encoded exon 19 (LocusLink ID 7158)
Purification Antigen affinity chromatography
Form Liquid
Storage Buffer PBS, 0.02% sodium azide
Storage temperature Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Temperature Ice
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