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Anti-ATP7B Rabbit Polyclonal Antibody

Dodávateľ: Thermo Fisher Scientific
PIEAPA116583EA 0 EUR
PIEAPA116583
Anti-ATP7B Rabbit Polyclonal Antibody
Protilátky
Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended. Suggested positive control: HuH7 hepatocarcinoma cell extracts, antigen standard for ATP7B (transient overexpression lysate). ATP7b is an important protein for copper transport and elimination of excess copper from the body. ATP7b transports metals in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene; A is found in the liver, kidney, and brain, the shorter form B is found in brain tissue, and the third isoform, known as WND/140 KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilson's disease, an inherited disorder causing copper poisoning in the brain and liver.

Type: Primary
Antigen: ATP7B
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Rat, Mouse
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