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Anti-ATP7B Rabbit Polyclonal Antibody

Dodávateľ: Thermo Scientific
Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended. Suggested positive control: HuH7 hepatocarcinoma cell extracts, antigen standard for ATP7B (transient overexpression lysate). ATP7b is an important protein for copper transport and elimination of excess copper from the body. ATP7b transports metals in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene; A is found in the liver, kidney, and brain, the shorter form B is found in brain tissue, and the third isoform, known as WND/140 KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilson's disease, an inherited disorder causing copper poisoning in the brain and liver.

Type: Primary
Antigen: ATP7B
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Rat, Mouse



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100 µL 100 µl PIEAPA116583 Blocked
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ŠPECIFIKÁCIE

Antigen symbol ATP7B
Antigen name ATPase, Cu++ transporting, beta polypeptide
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ImmunoChemistry Yes
ImmunoPrecipitation Yes
ImmunoFluorescence Yes
Antigen synonyms WND, RP11-327P2.3, WD, PWD, WC1
Gene ID 11979, 540, 24218
Concentration 1 mg/ml
Immunogen Synthetic peptide made to an internal sequence nearer the N-terminus of human ATP7b.
Purification Antigen affinity chromatography
Form Liquid
Storage Buffer tris citrate, 0.02% sodium azide, pH 7-8
Storage temperature 4° C, do not freeze
Shipping Temperature Ice
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