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Anti-CTR1 Rabbit Polyclonal Antibody

Dodávateľ: Thermo Scientific
Suggested positive control: human breast cancer and kidney tissue. The trace metal copper (Cu) plays a crucial role in mammalian cells as a cofactor for many enzymes. Cu-related genetic diseases, such as Menkes disease and Wilson disease, arise from a lack of Cu homeostasis in mammalian cells. CTR1 is a high-affinity copper-uptake protein. The C-terminal domain is similar to the Raf family of protein kinases, but it's first two-thirds encodes a novel protein domain. CTR1 provides the primary avenue for copper uptake in mammalian cells, thereby, affecting Cu homeostasis and embryonic development.

Type: Primary
Antigen: CTR1
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Rat, Porcine, Mouse, Xenopus laevis, Zebrafish

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100 µL 100 µl PIEAPA116586 Blocked
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Antigen symbol CTR1
Antigen name Copper Transporter 1
Reactivity Zebrafish, Porcine, Mouse, Rat, Human, Xenopus laevis
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western blot Yes
ImmunoChemistry Yes
ImmunoFluorescence Yes
Antigen synonyms hCTR1, COPT1, copper transporter 1, CTR1, solute carrier family 31 (copper tansporters) member 1
Gene ID 171135, 397186, 1317, 403028, 20529, 379422
Concentration 1 mg/ml
Immunogen Synthetic peptide of C-terminal region of human CTR1.
Purification Antigen affinity chromatography
Form Liquid
Storage buffer tris phosphate, tris citrate, 0.1% sodium azide, pH 7-8
Storage temperature 4° C, do not freeze
Shipping temperature Ice
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