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Anti-LOX Rabbit Polyclonal Antibody

Dodávateľ: Thermo Scientific
This antibody is 92% homologous to chicken, zebrafish, and xenopus. Lysyl oxidase (LOX), a copper-containing amine oxidase, belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. It plays a vital role in the formation and repair of the extra cellular matrix. As well, LOX is a multifunctional enzyme having diverse biological functions such as developmental regulation, tumor suppression, cell motility and cellular senescence. The secreted form of LOX is responsible for the invasive properties of hypoxic human cancer cells. Thus, it is essential for hypoxia-induced metastasis and is a good therapeutic target for preventing and treating metastases.

Type: Primary
Antigen: LOX
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse, Human, Bovine, Rat, Porcine



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OBJEDNAŤ

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50 µL 50 µl PIEAPA116955 Blocked
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ŠPECIFIKÁCIE

Antigen symbol LOX
Antigen name Lysyl oxidase
Reactivity Mouse, Rat, Porcine, Bovine, Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ImmunoChemistry Yes
Antigen synonyms EC 1.4.3.13 antibody, Protein-lysine 6-oxidase antibody, Lysyl oxidase antibody.
Gene ID 16948, 24914, 100525278, 280841, 4015
Concentration 1 mg/ml
Immunogen Cocktail of two synthetic peptides between amino acids 300-350 and amino acids 200-300 of the human LOX protein.
Purification Affinity chromatography
Form Liquid
Storage Buffer PBS, 0.02% sodium azide
Storage temperature -20° C, Avoid Freeze/Thaw Cycles
Shipping Temperature Ice
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