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Anti-TNFRSF8 Mouse Monoclonal Antibody (R-PE) [clone: CD30/412]

Dodávateľ: Biotium
BNCR0412-250EA 409.15 EUR
BNCR0412-250
Anti-TNFRSF8 Mouse Monoclonal Antibody (R-PE) [clone: CD30/412]
Protilátky
Recognizes a single chain glycoprotein of 105/120 kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90 kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120 kDa glycoprotein. In Hodgkin's disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).

Type: Primary
Antigen: TNFRSF8
Clonality: Monoclonal
Clone: CD30/412
Conjugation: R-PE
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
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