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Anti-CHGA Mouse Monoclonal Antibody (CF488A) [clone: CHGA/765]

Dodávateľ: Biotium

BNC880765-100EA 215.69 EUR
BNC880765-100 BNC880765-500
Anti-CHGA Mouse Monoclonal Antibody (CF488A) [clone: CHGA/765]
Protilátky
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

Type: Primary
Antigen: CHGA
Clonality: Monoclonal
Clone: CHGA/765
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG2a kappa
Reactivity: Human
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