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Anti-PTPRC Mouse Monoclonal Antibody (CF640R) [clone: PTPRC/1147]

Dodávateľ: Biotium

BNC401147-500EA 595.03 EUR
BNC401147-500 BNC401147-100
Anti-PTPRC Mouse Monoclonal Antibody (CF640R) [clone: PTPRC/1147]
Protilátky
CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.

Type: Primary
Antigen: PTPRC
Clonality: Monoclonal
Clone: PTPRC/1147
Conjugation: CF640R
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
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