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Anti-SPHK1 Rabbit Polyclonal Antibody

Dodávateľ: ProSci Inc.
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Sphingosine kinase (SPHK) phosphorylates sphingosine to form a bioactive lipid mediate, sphingosine 1-phosphate (S1P or SPP). S1P is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival while extracellularly it is a ligand for EDG 1. Expression of SPHK1 and subsequent production of S1P promotes the G1-S transition, protects cells from apoptosis, stimulates migration and angiogenesis, and induces tumor formation in mice.

SPHK1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.

PBS, 0.1% sodium azide.

PBS, 0.1% sodium azide.

Aliquot and store at -80°C. Avoid multiple freeze-thaw cycles.

Type:
Antigen: SPHK1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Gorilla, Human


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Veľkosť Pk Číslo v katalógu VWR Množstvo
50 µg 50 µG PRSI48-206
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ŠPECIFIKÁCIE

Antigen symbol SPHK1
Antigen name Sphingosine Kinase 1
Reactivity Human, Gorilla
Conjugation Unconjugated
Clonality Polyclonal
Host Rabbit
ImmunoChemistry Yes
Antigen synonyms SPK, SPHK, SPHK 1, sphingosine kinase 1, SK1, SK 1, SPK 1, SPK1.
Immunogen SPHK1 antibody was raised against a peptide located in the N-Terminal domain of SPHK1 (Human).
Form Liquid
Tested applications Immunoaffinity Chromatography
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