EDC-HCl (N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride) crosslinker
Dodávateľ: G Bioscienes
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Nebezpečí
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Synonymá:
EDC HCl
, EDC
EDC is a heterobifunctional, water-soluble, zero-length carbodiimide crosslinker that is used to couple carboxyl groups to primary amines. EDC activates carboxyl groups first and forms amine reactive O-acylisourea imtermediate that spontaneously reacts with primary amines to form an amide bond and isourea by-product.
The unstable nature of the intermediate in aqueous solutions makes 2-step coupling, however in conjunction with N-hydroxysuccinimide, a 2-step coupling is possible.
EDC is ideal for peptide immobilization and hapten-carrier protein conjugation
Vzorec:
C₈H₁₇N₃·HCl Mw: 191,7 g/mol Teplota tavenia: 112…113 °C Skladovacia teplota: Refrigerator |
Číslo MDL:
MFCD00012503 Číslo CAS: 25952-53-8 EINECS: 247-361-2 OSN: 2811 ADR: 6.1,III |
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